Synthesis of Heterocycles with AntiCoronavirus activity

KU Leuven , 1 or 2 semesters
In recent times several products discovered in our laboratory have shown mild to potent anticoronavirus activity. In this work we prose to synthesize analogs to get a structure-activity relationship.
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Synthesis of Heterocycles with AntiCoronavirus activity
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For reasons of intellectual property, we do not divulge here the details about the structures that lead to biological activity, nor the strategies to improve those activities. The project is related to heterocyclic chemistry and classical medicinal chemistry. We collaborate with the Rega institute for biological activity.

  • The project is available in Fall and Spring semester.
  • Number of places available: 1 or 2 per semester.

Prerequisites

  • High level undergraduate student.
  • Minimum GPA 3.4

Faculty Department

The Department of Chemistry (Faculty of Science) at KU Leuven University is involved in the organization courses of Bachelor/master of:

  • Chemistry 
  • Biochemistry and Biotechnology (the latter together with the department of Biology). 
  • The Department houses a staff of about 30 professors and has four divisions:
  • Molecular Design and Synthesis
  • Molecular and Nanomaterials
  • Quantum Chemistry and Physical chemistry
  • Biochemistry, Molecular and Structural Biology.

All my EuroScholars students were highly motivated and worked hard on their project together with a local mentor (Ph.D. student or postdoctoral associate). Quite often 1 or more publications resulted from their internship. Afterwards I stayed in touch with these students and learned that many of them pursued successful (academic) careers.

Read more about my experience in the program on this page.

Prof. Wim Dehaen

KU Leuven