Role of GRP78 in placentation

University of Geneva , 1 or 2 semesters
Glucose-regulated protein 78 (GRP78) is a chaperone protein involved in folding of proteins. It is necessary for the survival of stressed cells such as cancer cells and could induce invasion of tumour cells by an unknown mechanism that we would like to study.
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Role of GRP78 in placentation
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This protein is an endoplasmic reticulum-associated protein, but it was also observed on cell membranes on some cancer cells where it could mediate different signalling pathways involved in apoptosis, cell survival, cell proliferation and inflammation.

Students will contribute to research on the role of GRP78 in ovarian carcinogenesis. The methods used are or could be: cell culture, immunofluorescence, western blot, PCR. 

The team set up: 1PhD student, 1 Post doc, 2 lab technicians, 1 visiting professor, and the principal investigator.

Prerequisites

  • High level (3rd or 4th year) undergraduate student
  • Minimum GPA 3.4

Important note: 

Students must remain registered as an undergraduate student at their U.S. or Canadian home institution while participating in the program. The student's home institution must complete the Learning Agreement after acceptance into a project, even if credits will not be transferred to that institution. Transfer of credits is decided by the students' home institution.

Submitting an application, does not guarantee that the student will be offered a placement. The research projects are also available to our domestic degree students; therefore, projects may already be full at the time of applying. Final decision on your admission is solely taken by the Research Supervisor at the host institution.

I am currently a medical student, EuroScholars was a unique and important experience for me that set me apart from other applicants and ultimately helped me gain acceptance to a great medical school. The most important thing in my EuroScholars experience was exposure to various cultures in Europe. It helped me to develop personally and become more confident in my endeavors. My EuroScholars experience was a huge talking point during my medical school interviews.

Emily

University of Kansas

EuroScholars gave me a unique research experience that allowed me to get research positions the following year in undergrad and likely helped on my application to medical school. I valued the opportunity to be of a part research team at an institution abroad. They were like a family and they taught me so much more than just research skills. 

Kylie

University of Denver

Faculty Department

Faculty of Medicine / Dept. of Paediatrics, Gynaecology-Obstetrics

Gynaecology and Obstetrics department consists of groups of researchers whose main concern is the women patient. Thus, it directs its research projects towards new therapeutic solutions, improvement of tools for diagnosis, prevention, quality of care and psychosocial-oriented care.

Research presentation by Divyasri (Rutgers University)

Research presentation by Divyasri (Rutgers University)

Learn more about Divyasri's research project: Synthesis and optimization of MTX-Loaded NP for the treatment of Gestational Trophoblastic Neoplasia

Read more
Kylie (University of Denver)

Kylie (University of Denver)

Learn more about Kylie's joint publications: 

  • "The Dark Side of Cell Fusion".  
  • "Circulating GRP78 antibodies from ovarian cancer patients: a promising tool for cancer cell targeting drug delivery system?"
To joint publication