Molecular Cell Biology

Leiden University , 1 or 2 semesters
The section Molecular Cell Biology studies recognition of the environment by developing vertebrate cells. Zebrafish is used as the major test organism and compared with the human system.
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Molecular Cell Biology
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The research group of Professor Spaink studies recognition of microbes by animal cells. Zebrafish is used as the major test organism as a model for the human system. We focus on the function of microbial signal molecules that play a role in innate immunity. Our major objectives are to study the way in which cells can recognize the difference between signal molecules produced by pathogens and commensal microbes.In particular, we currently focus on the function of signal recognition in the innate immune system.
Research projects:

  1. Analysis of the role of Toll-like receptors and downstream signalling pathways in the recognition of microbial signal molecules that regulate innate immunity.
  2. The function of Toll-like receptors signaling in the regulation of host metabolism.
  • Number of places available: variable but limited per project and per semester.
  • Duration of participation in the project: minimum of 6 months.

Prerequisites

  • High level undergraduate student.
  • Minimum GPA 3.4
  • A profound knowledge of biochemistry and molecular biology is necessary.      

Through this experience, I was able to refine what I wanted to focus on in my future career and gain clarity on these decisions.

Adrian

Case Western Reserve University

Every employer that I have interviewed with has asked about my time in the Netherlands and I am beyond grateful to have the chance to talk about this experience.

Alexandra

Rutgers - The State University of New Jersey

Faculty Department

Faculty of Science /  Institute of Biology (IBL).

The Institute of Biology (IBL) brings together biologists working in many different subdisciplines (from ecology to evolutionary biology to molecular biology and metabolomics).

Research focuses on different levels, from molecule to cell, to organism to population. Studies deal with microorganisms, plants, fungi and animals (mainly insects and fish). Details can be found at the website of the IBL.

Research presentation by Liz (Colorado College)

Research presentation by Liz (Colorado College)

Learn more about Liz' research presentation: Functional Investigation of PE_PGRS Proteins and Their Role in Mycobacterial Virulence

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Research presentation by Adrian (Case Western Reserve University)

Research presentation by Adrian (Case Western Reserve University)

Learn more about Adrian's research project: Investigating the Biological function of proteins found in Mycobacteria in response to sterol exposure

Read more